People who receive organ transplant have to take a lot of pills to suppress immune response and make sure the organ is not rejected. New scientific research is showing that we could make the organs can be made immune tolerant.
Read the article in NewScientist
Marta Monteiro and colleagues at the University of Lisbon, Portugal, studied mice protected from the animal equivalent of multiple sclerosis by natural killer T-cells (NKT), a class of white blood cell which helps to control the immune system.
They discovered a population of NKT cells that have a gene that controls so-called regulatory T-cells, whose role is to suppress the immune response. The team labelled these so called NKTregs with fluorescent markers, then injected them back into mice. Unlike other types of regulatory T-cells, which move throughout the body, the NKTreg cells headed straight for the liver, where they suppressed immune function (Journal of Immunology, DOI: 10.4049/jimmunol.1000359).