Experimental drug AVI-7100 shows good potential against H1N1 virus

Two preclinical studies which evaluated AVI-7100 against a fully virulent pandemic H1N1 (swine flu) virus had promising results, says AVI Biopharma Inc. Data from the studies on ferrets (influenza effect on ferrets are close to the effect on humans) revealed statistically significant reductions in average viral titer vs. a saline control (placebo) and a Tamiflu control.
Seven days after infection, microscopic examinations of the ferrets’ lungs were done to assess the extent of regional tissue damage.

Pathology scores in both studies revealed only mild damage in the AVI-7100 treated ferrets, while damage was severe in both Tamiflu and saline controls.
Also read this press release from AVI BioPharma

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