Tag Archives: p53

Recently discovered protein TRIM 24 suppresses P24 and enhances chances of breast cancer

Posted on December 22, 2010 by rndsync

Reporting in the journal Nature, a team led by researchers at The University of Texas MD Anderson Cancer Center found that TRIM24 (tripartite motif-containing 24) pushes estrogen-responsive genes toward active expression. This expression, in turn, sets the stage for malignant … Continue reading →

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Amazing p53

Posted on December 19, 2010 by rndsync

P53 is an amazing protein. It’s role in Apoptosis and cellular repair is well known. In studies conducted on the fruit fly, researchers at IRB Barcelona headed by ICREA Professor Marco Milan have revealed that organs have the molecular mechanisms … Continue reading →

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p53 protein and it’s role in cancer. Seems like timing is everything in it’s ability to suppress cancer

Posted on November 25, 2010 by rndsync

p53 protein is encoded by TP53 gene in humans. It’s also known as tumor suppressor. P53 has many anticancer mechanisms, and plays a role in apoptosis, genetic stability, and inhibition of angiogenesis. In its anti-cancer role, p53 works through several … Continue reading →

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p21 protein – more wonders – this time may prevent AIDS

Posted on November 13, 2010 by rndsync

p21 protein is a cyclin-dependent inhibitor. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. … Continue reading →

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Stem cells can turn cancerous. But a new gene can prevent stem cells from turning cancerous!

Posted on October 16, 2010 by rndsync

Stem cells possess amazing ability to multiply but more importantly they can differentiate into other cells. This ability is called pluripotent. But they also have a darker side. They can turn cancerous except the presence of the protein ARTS (Apoptosis … Continue reading →

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Cancer recurs in patients treated with radiation. Scientists may have found clues to why.

Posted on August 1, 2010 by rndsync

puzzle of p53 behavior. Lack of “puma” protein should have caused cancer to be pervasive but it has the opposite effect. What gives? Nature has a way of surprising you when you think you got it all understood. Complex systems … Continue reading →

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