Category Archives: cancer

Telomerase inhibitor PINX1 is a key tumor suppressor

Posted on March 23, 2011 by rndsync

Telomeres are ends of choromosomes. For cell division to start and complete ends of chromosomes are essential. Without these, cell can’t divide any more. Each cell can divide a finite number of times before it’s done. It acts like a … Continue reading →

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Anti-malirial drug artensuate alone or combined with other cancer therapy effective in killing cancer cells especially if used in short bursts with drug free periods

Posted on January 9, 2011 by rndsync

Scientists investigating the cancer-fighting properties of artesunate a drug commonly used to treat malaria have found early evidence that combining it with an existing cancer drug has the potential to make each drug more effective than when used alone. The … Continue reading →

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Stupid science – Reductionists think they can solve something Biologists are unable to crack

Posted on December 27, 2010 by rndsync

The fight with Cancer has now been going on for several decades. Slowly but steadily scientists (biologists) are understanding and getting good picture of cancer, how it progresses, what signals and genes it suppresses to prevent detection and apoptosis. However, … Continue reading →

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Exercise is good for you! AMPK role in cell recycling may explain why AMPK plays an important role in metabolic disorders

Posted on December 24, 2010 by rndsync

AMPK (Adenosine monophosphate – activated protein kinase) is an amazing enzyme. It plays critical role in cellular energy homeostasis – maintaining balance of energy production and consumption in the cell by regulating ATP generation. When the process of autophagy is defective, cells … Continue reading →

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Recently discovered protein TRIM 24 suppresses P24 and enhances chances of breast cancer

Posted on December 22, 2010 by rndsync

Reporting in the journal Nature, a team led by researchers at The University of Texas MD Anderson Cancer Center found that TRIM24 (tripartite motif-containing 24) pushes estrogen-responsive genes toward active expression. This expression, in turn, sets the stage for malignant … Continue reading →

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Do we differ from Chimpanzees in genetic make up?

Posted on December 17, 2010 by rndsync

The popular answer has been that the difference is tiny and we share 98% of the genome with Chimpanzee. However, it’s important to see where these differences lie even though it’s only 2%. In genetics, even a few 1000 base … Continue reading →

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p53 protein and it’s role in cancer. Seems like timing is everything in it’s ability to suppress cancer

Posted on November 25, 2010 by rndsync

p53 protein is encoded by TP53 gene in humans. It’s also known as tumor suppressor. P53 has many anticancer mechanisms, and plays a role in apoptosis, genetic stability, and inhibition of angiogenesis. In its anti-cancer role, p53 works through several … Continue reading →

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Smoking is injurious to your health and everyone around you. So stop it!!!

Posted on November 25, 2010 by rndsync

Smoking is banned in most public places. That’s great for non-smokers and even for smokers. Second hand smoke is harmful. Statistics show that this is a fact. More statistics about Tobacco Use •Worldwide, tobacco use causes nearly 5 million deaths … Continue reading →

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p21 protein – more wonders – this time may prevent AIDS

Posted on November 13, 2010 by rndsync

p21 protein is a cyclin-dependent inhibitor. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. … Continue reading →

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Benign tumors can be transformed into cancer by virus

Posted on November 11, 2010 by rndsync

A new discovery by UNC scientists describes how cells infected by the Epstein-Barr virus (EBV) produce small vesicles or sacs called exosomes, changing their cellular "cargo" of proteins and RNA. This altered exosome enters cells and can change the growth … Continue reading →

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